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High Glucose Induces the Loss of Retinal Pericytes Partly via NLRP3-Caspase-1-GSDMD-Mediated Pyroptosis

Diabetic retinopathy (DR) is one of the hallmark complications of diabetes and a leading cause of vision loss in adults. Retinal pericyte death seems to be a prominent feature in the onset of DR. Pyroptosis is an inflammatory form of programmed cell death, defined as being caspase-gasdermin-D (GSDMD...

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Detalhes bibliográficos
Publicado no:Biomed Res Int
Main Authors: Gan, Jinhua, Huang, Maomao, Lan, Genyin, Liu, Li, Xu, Fangyuan
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7201508/
https://ncbi.nlm.nih.gov/pubmed/32420343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/4510628
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