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Synthesis and Reactions of 3,3-Difluoro-2-exo-methylidene Indolines
[Image: see text] A dearomative electrophilic fluorination of 2-methylindoles is reported, delivering 3,3-difluoroindolines bearing an exomethylidene. The model substrate was synthesized on up to a 20 mmol scale and was purified by a practical recrystallization as a crystalline bench-stable, yet rea...
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| Publicado en: | Org Lett |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Chemical Society
2020
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7201399/ https://ncbi.nlm.nih.gov/pubmed/32276536 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.0c01175 |
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