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Enzyme-linked oligonucleotide hybridization assay for direct oligo measurement in blood

Small oligonucleotides (oligos) are increasingly being utilized as diagnostics or treatments for disease. An impediment to broader use is the ability to readily measure oligos in biological fluids. Here, we describe a very straightforward assay with detection in the sub-picomole range that does not...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Biol Methods Protoc
Hauptverfasser: Lorenson, Mary Y, Chen, Kuan-Hui Ethan, Walker, Ameae M
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7200967/
https://ncbi.nlm.nih.gov/pubmed/32395619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biomethods/bpy014
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