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Enzyme-linked oligonucleotide hybridization assay for direct oligo measurement in blood

Small oligonucleotides (oligos) are increasingly being utilized as diagnostics or treatments for disease. An impediment to broader use is the ability to readily measure oligos in biological fluids. Here, we describe a very straightforward assay with detection in the sub-picomole range that does not...

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Bibliografiske detaljer
Udgivet i:Biol Methods Protoc
Main Authors: Lorenson, Mary Y, Chen, Kuan-Hui Ethan, Walker, Ameae M
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7200967/
https://ncbi.nlm.nih.gov/pubmed/32395619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biomethods/bpy014
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