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Enzyme-linked oligonucleotide hybridization assay for direct oligo measurement in blood

Small oligonucleotides (oligos) are increasingly being utilized as diagnostics or treatments for disease. An impediment to broader use is the ability to readily measure oligos in biological fluids. Here, we describe a very straightforward assay with detection in the sub-picomole range that does not...

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Dades bibliogràfiques
Publicat a:Biol Methods Protoc
Autors principals: Lorenson, Mary Y, Chen, Kuan-Hui Ethan, Walker, Ameae M
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7200967/
https://ncbi.nlm.nih.gov/pubmed/32395619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biomethods/bpy014
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