TNF-alpha inhibition ameliorates HDV-induced liver damage in a mouse model of acute severe infection

BACKGROUND & AIMS: HDV infection induces the most severe form of human viral hepatitis. However, the specific reasons for the severity of the disease remain unknown. Recently, we developed an HDV replication mouse model in which, for the first time, liver damage was detected. METHODS: HDV and HB...

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Veröffentlicht in:JHEP Rep
Hauptverfasser: Usai, Carla, Maestro, Sheila, Camps, Gracian, Olague, Cristina, Suárez-Amaran, Lester, Vales, Africa, Aragon, Tomas, Hommel, Mirja, Aldabe, Rafael, Gonzalez-Aseguinolaza, Gloria
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2020
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7200939/
https://ncbi.nlm.nih.gov/pubmed/32382723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhepr.2020.100098
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