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TNF-alpha inhibition ameliorates HDV-induced liver damage in a mouse model of acute severe infection

BACKGROUND & AIMS: HDV infection induces the most severe form of human viral hepatitis. However, the specific reasons for the severity of the disease remain unknown. Recently, we developed an HDV replication mouse model in which, for the first time, liver damage was detected. METHODS: HDV and HB...

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Detalhes bibliográficos
Publicado no:JHEP Rep
Main Authors: Usai, Carla, Maestro, Sheila, Camps, Gracian, Olague, Cristina, Suárez-Amaran, Lester, Vales, Africa, Aragon, Tomas, Hommel, Mirja, Aldabe, Rafael, Gonzalez-Aseguinolaza, Gloria
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7200939/
https://ncbi.nlm.nih.gov/pubmed/32382723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhepr.2020.100098
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