TNF-alpha inhibition ameliorates HDV-induced liver damage in a mouse model of acute severe infection

BACKGROUND & AIMS: HDV infection induces the most severe form of human viral hepatitis. However, the specific reasons for the severity of the disease remain unknown. Recently, we developed an HDV replication mouse model in which, for the first time, liver damage was detected. METHODS: HDV and HB...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:JHEP Rep
Autori principali: Usai, Carla, Maestro, Sheila, Camps, Gracian, Olague, Cristina, Suárez-Amaran, Lester, Vales, Africa, Aragon, Tomas, Hommel, Mirja, Aldabe, Rafael, Gonzalez-Aseguinolaza, Gloria
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2020
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7200939/
https://ncbi.nlm.nih.gov/pubmed/32382723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhepr.2020.100098
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