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A high-resolution description of β(1)-adrenergic receptor functional dynamics and allosteric coupling from backbone NMR
Signal transmission and regulation of G-protein-coupled receptors (GPCRs) by extra- and intracellular ligands occurs via modulation of complex conformational equilibria, but their exact kinetic details and underlying atomic mechanisms are unknown. Here we quantified these dynamic equilibria in the β...
Gorde:
| Argitaratua izan da: | Nat Commun |
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| Egile Nagusiak: | , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Nature Publishing Group UK
2020
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7200737/ https://ncbi.nlm.nih.gov/pubmed/32371991 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-15864-y |
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