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Quantification of tRNA fragments by electrochemical direct detection in small volume biofluid samples

Elevated levels of transfer RNA (tRNA) fragments were recently identified in plasma samples from people with epilepsy in advance of a seizure, indicting a potential novel class of circulating biomarker. Current methods for detection and quantitation of tRNA fragments (tRFs) include northern blotting...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: McArdle, Hazel, Hogg, Marion C., Bauer, Sebastian, Rosenow, Felix, Prehn, Jochen H. M., Adamson, Kellie, Henshall, David C., Spain, Elaine
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7200677/
https://ncbi.nlm.nih.gov/pubmed/32371908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-64485-4
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