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The F220C and F45L rhodopsin mutations identified in retinitis pigmentosa patients do not cause pathology in mice

Retinitis pigmentosa is a retinal degenerative disease that leads to blindness through photoreceptor loss. Rhodopsin is the most frequently mutated protein in this disease. While many rhodopsin mutations have well-understood consequences that lead to cell death, the disease association of several rh...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Lewis, Tylor R., Shores, Camilla R., Cady, Martha A., Hao, Ying, Arshavsky, Vadim Y., Burns, Marie E.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7200662/
https://ncbi.nlm.nih.gov/pubmed/32371886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-64437-y
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