GSDME-Dependent Incomplete Pyroptosis Permits Selective IL-1α Release under Caspase-1 Inhibition

Pyroptosis is a form of regulated cell death that is characterized by gasdermin processing and increased membrane permeability. Caspase-1 and caspase-11 have been considered to be essential for gasdermin D processing associated with inflammasome activation. In the present study, we found that NLRP3...

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Publicat a:iScience
Autors principals: Aizawa, Emi, Karasawa, Tadayoshi, Watanabe, Sachiko, Komada, Takanori, Kimura, Hiroaki, Kamata, Ryo, Ito, Homare, Hishida, Erika, Yamada, Naoya, Kasahara, Tadashi, Mori, Yoshiyuki, Takahashi, Masafumi
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7200307/
https://ncbi.nlm.nih.gov/pubmed/32361594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101070
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