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Cleavage of GSDME by caspase-3 determines lobaplatin-induced pyroptosis in colon cancer cells

Pyroptosis, a form of programmed cell death (PCD), has garnered increasing attention as it relates to innate immunity and diseases. However, the involvement of pyroptosis in the mechanism by which lobaplatin acts against colorectal cancer (CRC) is unclear. Our study revealed that treatment with loba...

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Dettagli Bibliografici
Pubblicato in:Cell Death Dis
Autori principali: Yu, Junhui, Li, Shan, Qi, Jie, Chen, Zilu, Wu, Yunhua, Guo, Jing, Wang, Kai, Sun, Xuejun, Zheng, Jianbao
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6389936/
https://ncbi.nlm.nih.gov/pubmed/30804337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1441-4
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