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Cleavage of GSDME by caspase-3 determines lobaplatin-induced pyroptosis in colon cancer cells

Pyroptosis, a form of programmed cell death (PCD), has garnered increasing attention as it relates to innate immunity and diseases. However, the involvement of pyroptosis in the mechanism by which lobaplatin acts against colorectal cancer (CRC) is unclear. Our study revealed that treatment with loba...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Yu, Junhui, Li, Shan, Qi, Jie, Chen, Zilu, Wu, Yunhua, Guo, Jing, Wang, Kai, Sun, Xuejun, Zheng, Jianbao
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6389936/
https://ncbi.nlm.nih.gov/pubmed/30804337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1441-4
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