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Genetic interaction of mammalian IFT-A paralogs regulates cilia disassembly, ciliary entry of membrane protein, Hedgehog signaling and embryogenesis

Primary cilia are sensory organelles that are essential for eukaryotic development and health. These antenna-like structures are synthesized by intraflagellar transport protein complexes, IFT-B and IFT-A, which mediate bi-directional protein trafficking along the ciliary axoneme. Here using mouse em...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Wang, Wei, Allard, Bailey A., Pottorf, Tana S., Wang, Henry H., Vivian, Jay L., Tran, Pamela V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7200294/
https://ncbi.nlm.nih.gov/pubmed/32167205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201902611R
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