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Zebrafish ift57, ift88, and ift172 intraflagellar transport mutants disrupt cilia but do not affect Hedgehog signaling

Cilia formation requires intraflagellar transport (IFT) proteins. Recent studies indicate that mammalian Hedgehog (Hh) signaling requires cilia. It is unclear, however, if the requirement for cilia and IFT proteins in Hh signaling represents a general rule for all vertebrates. Here we examine zebraf...

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Hlavní autoři: Lunt, Shannon C., Haynes, Tony, Perkins, Brian D.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2771627/
https://ncbi.nlm.nih.gov/pubmed/19517571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvdy.21999
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