A microfluidic chip enables isolation of exosomes and establishment of their protein profiles and associated signaling pathways in ovarian cancer

Due to limits on specificity and purity to allow for in-depth protein profiling, a standardized method for exosome isolation has yet to be established. In this study, we describe a novel, in-house microfluidic-based device to isolate exosomes from culture media and patient samples. This technology o...

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Vydáno v:Cancer Res
Hlavní autoři: Dorayappan, Kalpana Deepa Priya, Gardner, Miranda L., Hisey, Colin L., Zingarelli, Roman A., Smith, Brentley Q., Lightfoot, Michelle D.S., Gogna, Rajan, Flannery, Meghan M., Hays, John, Hansford, Derek J., Freitas, Michael A., Yu, Lianbo, Cohn, David E., Selvendiran, Karuppaiyah
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7200082/
https://ncbi.nlm.nih.gov/pubmed/31097475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-18-3538
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