A microfluidic chip enables isolation of exosomes and establishment of their protein profiles and associated signaling pathways in ovarian cancer

Due to limits on specificity and purity to allow for in-depth protein profiling, a standardized method for exosome isolation has yet to be established. In this study, we describe a novel, in-house microfluidic-based device to isolate exosomes from culture media and patient samples. This technology o...

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Bibliographic Details
Published in:Cancer Res
Main Authors: Dorayappan, Kalpana Deepa Priya, Gardner, Miranda L., Hisey, Colin L., Zingarelli, Roman A., Smith, Brentley Q., Lightfoot, Michelle D.S., Gogna, Rajan, Flannery, Meghan M., Hays, John, Hansford, Derek J., Freitas, Michael A., Yu, Lianbo, Cohn, David E., Selvendiran, Karuppaiyah
Format: Artigo
Language:Inglês
Published: 2019
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7200082/
https://ncbi.nlm.nih.gov/pubmed/31097475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-18-3538
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