High expression of JC polyomavirus-encoded microRNAs in progressive multifocal leukoencephalopathy tissues and its repressive role in virus replication

JC polyomavirus (JCPyV, JCV) causes progressive multifocal leukoencephalopathy (PML) in immunocompromised hosts. JCPyV replicates in oligodendrocytes within the brain tissue of patients with PML. The JCPyV genome encodes a microRNA (miRNA) in the region encoding the large T antigen. JCPyV-encoded mi...

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Gepubliceerd in:PLoS Pathog
Hoofdauteurs: Takahashi, Kenta, Sato, Yuko, Sekizuka, Tsuyoshi, Kuroda, Makoto, Suzuki, Tadaki, Hasegawa, Hideki, Katano, Harutaka
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2020
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7200015/
https://ncbi.nlm.nih.gov/pubmed/32324824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008523
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