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High expression of JC polyomavirus-encoded microRNAs in progressive multifocal leukoencephalopathy tissues and its repressive role in virus replication

JC polyomavirus (JCPyV, JCV) causes progressive multifocal leukoencephalopathy (PML) in immunocompromised hosts. JCPyV replicates in oligodendrocytes within the brain tissue of patients with PML. The JCPyV genome encodes a microRNA (miRNA) in the region encoding the large T antigen. JCPyV-encoded mi...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Takahashi, Kenta, Sato, Yuko, Sekizuka, Tsuyoshi, Kuroda, Makoto, Suzuki, Tadaki, Hasegawa, Hideki, Katano, Harutaka
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7200015/
https://ncbi.nlm.nih.gov/pubmed/32324824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008523
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