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Cryo-EM reconstruction of a VPS13 fragment reveals a long groove to channel lipids between membranes
A single particle cryo-EM reconstruction of an ∼160-kD N-terminal fragment of the lipid transport protein VPS13 reveals an ∼160-Å long channel lined with hydrophobic residues suitable for solubilizing multiple lipid fatty acid moieties. The structure suggests that VPS13 and related proteins, like th...
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| Publicat a: | J Cell Biol |
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| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Rockefeller University Press
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7199853/ https://ncbi.nlm.nih.gov/pubmed/32182622 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.202001161 |
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