Griffithsin Inhibits Nipah Virus Entry and Fusion and Can Protect Syrian Golden Hamsters From Lethal Nipah Virus Challenge

Nipah virus (NiV) is a highly pathogenic zoonotic paramyxovirus that causes fatal encephalitis and respiratory disease in humans. There is currently no approved therapeutic for human use against NiV infection. Griffithsin (GRFT) is high-mannose oligosaccharide binding lectin that has shown in vivo b...

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Vydáno v:J Infect Dis
Hlavní autoři: Lo, Michael K, Spengler, Jessica R, Krumpe, Lauren R H, Welch, Stephen R, Chattopadhyay, Anasuya, Harmon, Jessica R, Coleman-McCray, JoAnn D, Scholte, Florine E M, Hotard, Anne L, Fuqua, Joshua L, Rose, John K, Nichol, Stuart T, Palmer, Kenneth E, O’Keefe, Barry R, Spiropoulou, Christina F
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2020
Témata:
Supplement Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7199786/
https://ncbi.nlm.nih.gov/pubmed/32037447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiz630
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