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Single-Dose Replication-Defective VSV-based Nipah Virus Vaccines Provide Protection from Lethal Challenge in Syrian Hamsters

Nipah virus (NiV) continues to cause outbreaks of fatal human encephalitis due to spillover from its bat reservoir. We determined that a single dose of replication-defective vesicular stomatitis virus (VSV)-based vaccine vectors expressing either the NiV fusion (F) or attachment (G) glycoproteins pr...

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Detalhes bibliográficos
Main Authors: Lo, Michael K., Bird, Brian H., Chattopadhyay, Anasuya, Drew, Clifton P., Martin, Brock E., Coleman, Joann D., Rose, John K., Nichol, Stuart T., Spiropoulou, Christina F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3874889/
https://ncbi.nlm.nih.gov/pubmed/24184127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2013.10.012
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