Evaluation of a Single-Dose Nucleoside-Modified Messenger RNA Vaccine Encoding Hendra Virus-Soluble Glycoprotein Against Lethal Nipah virus Challenge in Syrian Hamsters

In the absence of approved vaccines and therapeutics for use in humans, Nipah virus (NiV) continues to cause fatal outbreaks of encephalitis and respiratory disease in Bangladesh and India on a near-annual basis. We determined that a single dose of a lipid nanoparticle nucleoside-modified messenger...

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Detalhes bibliográficos
Publicado no:J Infect Dis
Main Authors: Lo, Michael K, Spengler, Jessica R, Welch, Stephen R, Harmon, Jessica R, Coleman-McCray, JoAnn D, Scholte, Florine E M, Shrivastava-Ranjan, Punya, Montgomery, Joel M, Nichol, Stuart T, Weissman, Drew, Spiropoulou, Christina F
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Supplement Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7368163/
https://ncbi.nlm.nih.gov/pubmed/31751453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiz553
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