Wird geladen...

Structural Basis for Potent Neutralization of Betacoronaviruses by Single-Domain Camelid Antibodies

Coronaviruses make use of a large envelope protein called spike (S) to engage host cell receptors and catalyze membrane fusion. Because of the vital role that these S proteins play, they represent a vulnerable target for the development of therapeutics. Here, we describe the isolation of single-doma...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Cell
Hauptverfasser: Wrapp, Daniel, De Vlieger, Dorien, Corbett, Kizzmekia S., Torres, Gretel M., Wang, Nianshuang, Van Breedam, Wander, Roose, Kenny, van Schie, Loes, Hoffmann, Markus, Pöhlmann, Stefan, Graham, Barney S., Callewaert, Nico, Schepens, Bert, Saelens, Xavier, McLellan, Jason S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier Inc. 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7199733/
https://ncbi.nlm.nih.gov/pubmed/32375025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2020.04.031
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!