The Ratiometric Transcript Signature MX2/GPR183 Is Consistently Associated With RTS,S-Mediated Protection Against Controlled Human Malaria Infection

The RTS,S/AS01 vaccine provides partial protection against Plasmodium falciparum infection but determinants of protection and/or disease are unclear. Previously, anti-circumsporozoite protein (CSP) antibody titers and blood RNA signatures were associated with RTS,S/AS01 efficacy against controlled h...

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Publicat a:Front Immunol
Autors principals: Du, Ying, Thompson, Ethan G., Muller, Julius, Valvo, Joseph, Braun, Jackie, Shankar, Smitha, van den Berg, Robert A., Jongert, Erik, Dover, Drew, Sadoff, Jerald, Hendriks, Jenny, Gardner, Malcolm J., Ballou, W. Ripley, Regules, Jason A., van der Most, Robbert, Aderem, Alan, Ockenhouse, Christian F., Hill, Adrian V., Wille-Reece, Ulrike, Zak, Daniel E.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2020
Matèries:
Immunology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7199517/
https://ncbi.nlm.nih.gov/pubmed/32411130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00669
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