Comprehensive Characterization of Transcriptional Activity during Influenza A Virus Infection Reveals Biases in Cap-Snatching of Host RNA Sequences

Macrophages in the lung detect and respond to influenza A virus (IAV), determining the nature of the immune response. Using terminal-depth cap analysis of gene expression (CAGE), we quantified transcriptional activity of both host and pathogen over a 24-h time course of IAV infection in primary huma...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Clohisey, Sara, Parkinson, Nicholas, Wang, Bo, Bertin, Nicolas, Wise, Helen, Tomoiu, Andru, Summers, Kim M., Hendry, Ross W., Carninci, Piero, Forrest, Alistair R. R., Hayashizaki, Yoshihide, Digard, Paul, Hume, David A., Baillie, J. Kenneth
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7199409/
https://ncbi.nlm.nih.gov/pubmed/32161175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01720-19
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