Magnesium protects against cisplatin-induced acute kidney injury by regulating platinum accumulation

Despite its success as a potent antineoplastic agent, ∼25% of patients receiving cisplatin experience acute kidney injury (AKI) and must discontinue therapy. Impaired magnesium homeostasis has been linked to cisplatin-mediated AKI, and because magnesium deficiency is widespread, we examined the effe...

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Detalhes bibliográficos
Publicado no:Am J Physiol Renal Physiol
Main Authors: Solanki, Malvika H., Chatterjee, Prodyot K., Gupta, Madhu, Xue, Xiangying, Plagov, Andrei, Metz, Margot H., Mintz, Rachel, Singhal, Pravin C., Metz, Christine N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2014
Assuntos:
CALL FOR PAPERS | Novel Therapeutics in Renal Diseases
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7199227/
https://ncbi.nlm.nih.gov/pubmed/24944268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00127.2014
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