Activation of the cholinergic anti-inflammatory pathway by GTS-21 attenuates cisplatin-induced acute kidney injury in mice

Acute kidney injury (AKI) is the most common side effect of cisplatin, a widely used chemotherapy drug. Although AKI occurs in up to one third of cancer patients receiving cisplatin, effective renal protective strategies are lacking. Cisplatin targets renal proximal tubular epithelial cells leading...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Chatterjee, Prodyot K., Yeboah, Michael M., Solanki, Malvika H., Kumar, Gopal, Xue, Xiangying, Pavlov, Valentin A., Al-Abed, Yousef, Metz, Christine N.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5708817/
https://ncbi.nlm.nih.gov/pubmed/29190774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0188797
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