Activation PDGFR-α/AKT Mediated Signaling Pathways in Oral Squamous Cell Carcinoma by Mesenchymal Stem/Stromal Cells Promotes Anti-apoptosis and Decreased Sensitivity to Cisplatin

Desmoplasia, a hallmark of a head and neck cancer, has both biologic and physiologic effects on cancer progression and chemotherapeutic response. Mesenchymal stem/stromal cells (MSCs), also known as mesenchymal stromal progenitor cells, have been shown to play a role in cancer progression, alter apo...

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Опубликовано в: :Front Oncol
Главные авторы: Wang, Jia, Cui, Ruwen, Clement, Cecila G., Nawgiri, Ranjana, Powell, Don W., Pinchuk, Irina V., Watts, Tammara L.
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2020
Предметы:
Oncology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7199219/
https://ncbi.nlm.nih.gov/pubmed/32411595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.00552
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