PDGF-AA mediates mesenchymal stromal cell chemotaxis to the head and neck squamous cell carcinoma tumor microenvironment

BACKGROUND: The robust desmoplasia associated with head and neck squamous cell carcinoma (HNSCC) suggests that the tumor microenvironment may be an important component in the pathophysiology of this cancer. Moreover, the high recurrence rate and poor clinical response to chemotherapy and radiation t...

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Detalhes bibliográficos
Publicado no:J Transl Med
Main Authors: Watts, Tammara L., Cui, Ruwen, Szaniszlo, Peter, Resto, Vicente A., Powell, Don W., Pinchuk, Irina V.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5146849/
https://ncbi.nlm.nih.gov/pubmed/27931212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-016-1091-6
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