O-Acetylated Chemical Reporters of Glycosylation Can Display Metabolism-Dependent Background Labeling of Proteins but Are Generally Reliable Tools for the Identification of Glycoproteins

Monosaccharide analogs bearing bioorthogonal functionalities, or metabolic chemical reporters (MCRs) of glycosylation, have been used for approximately two decades for the visualization and identification of different glycoproteins. More recently, proteomics analyses have shown that per-O-acetylated...

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Detalhes bibliográficos
Publicado no:Front Chem
Main Authors: Darabedian, Narek, Yang, Bo, Ding, Richie, Cutolo, Giuliano, Zaro, Balyn W., Woo, Christina M., Pratt, Matthew R.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Chemistry
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7198827/
https://ncbi.nlm.nih.gov/pubmed/32411667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2020.00318
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