Paternal restraint stress affects offspring metabolism via ATF-2 dependent mechanisms in Drosophila melanogaster germ cells

Paternal environmental factors can epigenetically influence gene expressions in offspring. We demonstrate that restraint stress, an experimental model for strong psychological stress, to fathers affects the epigenome, transcriptome, and metabolome of offspring in a MEKK1-dATF2 pathway-dependent mann...

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Publicado en:Commun Biol
Autores principales: Seong, Ki-Hyeon, Ly, Nhung Hong, Katou, Yuki, Yokota, Naoko, Nakato, Ryuichiro, Murakami, Shinnosuke, Hirayama, Akiyoshi, Fukuda, Shinji, Kang, Siu, Soga, Tomoyoshi, Shirahige, Katsuhiko, Ishii, Shunsuke
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7198565/
https://ncbi.nlm.nih.gov/pubmed/32367035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-020-0935-z
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