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Replication-Coupled PCNA Unloading by the Elg1 Complex Occurs Genome-wide and Requires Okazaki Fragment Ligation

The sliding clamp PCNA is a crucial component of the DNA replication machinery. Timely PCNA loading and unloading are central for genome integrity and must be strictly coordinated with other DNA processing steps during replication. Here, we show that the S. cerevisiae Elg1 replication factor C-like...

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Podrobná bibliografie
Vydáno v:Cell Rep
Hlavní autoři: Kubota, Takashi, Katou, Yuki, Nakato, Ryuichiro, Shirahige, Katsuhiko, Donaldson, Anne D.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cell Press 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4534484/
https://ncbi.nlm.nih.gov/pubmed/26212319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.06.066
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