The PCNA unloader Elg1 promotes recombination at collapsed replication forks in fission yeast

Protein-DNA complexes can impede DNA replication and cause replication fork collapse. Whilst it is known that homologous recombination is deployed in such instances to restart replication, it is unclear how a stalled fork transitions into a collapsed fork at which recombination proteins can load. Pr...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:eLife
Prif Awduron: Tamang, Sanjeeta, Kishkevich, Anastasiya, Morrow, Carl A, Osman, Fekret, Jalan, Manisha, Whitby, Matthew C
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: eLife Sciences Publications, Ltd 2019
Pynciau:
Chromosomes and Gene Expression
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6544435/
https://ncbi.nlm.nih.gov/pubmed/31149897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.47277
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