Factors affecting template switch recombination associated with restarted DNA replication

Homologous recombination helps ensure the timely completion of genome duplication by restarting collapsed replication forks. However, this beneficial function is not without risk as replication restarted by homologous recombination is prone to template switching (TS) that can generate deleterious ge...

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Bibliographic Details
Published in:eLife
Main Authors: Jalan, Manisha, Oehler, Judith, Morrow, Carl A, Osman, Fekret, Whitby, Matthew C
Format: Artigo
Language:Inglês
Published: eLife Sciences Publications, Ltd 2019
Subjects:
Chromosomes and Gene Expression
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6358216/
https://ncbi.nlm.nih.gov/pubmed/30667359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.41697
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