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Factors affecting template switch recombination associated with restarted DNA replication

Homologous recombination helps ensure the timely completion of genome duplication by restarting collapsed replication forks. However, this beneficial function is not without risk as replication restarted by homologous recombination is prone to template switching (TS) that can generate deleterious ge...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:eLife
Prif Awduron: Jalan, Manisha, Oehler, Judith, Morrow, Carl A, Osman, Fekret, Whitby, Matthew C
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: eLife Sciences Publications, Ltd 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6358216/
https://ncbi.nlm.nih.gov/pubmed/30667359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.41697
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