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Recombination occurs within minutes of replication blockage by RTS1 producing restarted forks that are prone to collapse

The completion of genome duplication during the cell cycle is threatened by the presence of replication fork barriers (RFBs). Following collision with a RFB, replication proteins can dissociate from the stalled fork (fork collapse) rendering it incapable of further DNA synthesis unless recombination...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:eLife
Päätekijät: Nguyen, Michael O, Jalan, Manisha, Morrow, Carl A, Osman, Fekret, Whitby, Matthew C
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: eLife Sciences Publications, Ltd 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4407270/
https://ncbi.nlm.nih.gov/pubmed/25806683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.04539
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