Paternal restraint stress affects offspring metabolism via ATF-2 dependent mechanisms in Drosophila melanogaster germ cells

Paternal environmental factors can epigenetically influence gene expressions in offspring. We demonstrate that restraint stress, an experimental model for strong psychological stress, to fathers affects the epigenome, transcriptome, and metabolome of offspring in a MEKK1-dATF2 pathway-dependent mann...

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Detalhes bibliográficos
Publicado no:Commun Biol
Main Authors: Seong, Ki-Hyeon, Ly, Nhung Hong, Katou, Yuki, Yokota, Naoko, Nakato, Ryuichiro, Murakami, Shinnosuke, Hirayama, Akiyoshi, Fukuda, Shinji, Kang, Siu, Soga, Tomoyoshi, Shirahige, Katsuhiko, Ishii, Shunsuke
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7198565/
https://ncbi.nlm.nih.gov/pubmed/32367035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-020-0935-z
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