TSPO Versus P2X7 as a Target for Neuroinflammation: An In Vitro and In Vivo Study

Neuroinflammation is important in amyotrophic lateral sclerosis (ALS). The P2X7 receptor (P2X7R) is a promising target for neuroinflammation. The objective of this study was to compare (18)F-DPA714, a second-generation translocator protein tracer, with (11)C-JNJ717, a novel P2X7R tracer, in vitro an...

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Detalles Bibliográficos
Publicado en:J Nucl Med
Main Authors: Van Weehaeghe, Donatienne, Van Schoor, Evelien, De Vocht, Joke, Koole, Michel, Attili, Bala, Celen, Sofie, Declercq, Lieven, Thal, Dietmar R., Van Damme, Philip, Bormans, Guy, Van Laere, Koen
Formato: Artigo
Idioma:Inglês
Publicado: Society of Nuclear Medicine 2020
Assuntos:
Neurology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7198372/
https://ncbi.nlm.nih.gov/pubmed/31562223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.119.231985
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