Circadian sleep/wake-associated cells show dipeptide repeat protein aggregates in C9orf72-related ALS and FTLD cases

Motor-, behavior- and/or cognition-related symptoms are key hallmarks in patients with amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD) with TDP-43 pathology (FTLD-TDP), respectively. It has been reported that these patients also experience sleep disturbances, which m...

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Dettagli Bibliografici
Pubblicato in:Acta Neuropathol Commun
Autori principali: Dedeene, Lieselot, Van Schoor, Evelien, Vandenberghe, Rik, Van Damme, Philip, Poesen, Koen, Thal, Dietmar Rudolf
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2019
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6889626/
https://ncbi.nlm.nih.gov/pubmed/31791419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-019-0845-9
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