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Multiplexed Gene Expression Tuning with Orthogonal Synthetic Gene Circuits

[Image: see text] Understanding the individual and joint contribution of multiple protein levels toward a phenotype requires precise and tunable multigene expression control. Here we introduce a pair of mammalian synthetic gene circuits that linearly and orthogonally control the expression of two re...

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Xehetasun bibliografikoak
Argitaratua izan da:ACS Synth Biol
Egile Nagusiak: Szenk, Mariola, Yim, Terrence, Balázsi, Gábor
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Chemical Society 2020
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7197936/
https://ncbi.nlm.nih.gov/pubmed/32167761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acssynbio.9b00534
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