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Multiplexed Gene Expression Tuning with Orthogonal Synthetic Gene Circuits

[Image: see text] Understanding the individual and joint contribution of multiple protein levels toward a phenotype requires precise and tunable multigene expression control. Here we introduce a pair of mammalian synthetic gene circuits that linearly and orthogonally control the expression of two re...

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Bibliografiske detaljer
Udgivet i:ACS Synth Biol
Main Authors: Szenk, Mariola, Yim, Terrence, Balázsi, Gábor
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2020
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7197936/
https://ncbi.nlm.nih.gov/pubmed/32167761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acssynbio.9b00534
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