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Angiotensin‐converting enzyme 2 catalytic activity in human plasma is masked by an endogenous inhibitor

Angiotensin‐converting enzyme 2 (ACE2) is thought to act in an opposing manner to its homologue, angiotensin‐converting enzyme (ACE), by inactivating the vasoconstrictor peptide angiotensin II and generating the vasodilatory fragment, angiotensin(1–7). Both ACE and ACE2 are membrane‐bound ectoenzyme...

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Publicat a:Exp Physiol
Autors principals: Lew, Rebecca A., Warner, Fiona J., Hanchapola, Iresha, Yarski, Michael A., Manohar, Jay, Burrell, Louise M., Smith, A. Ian
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7197901/
https://ncbi.nlm.nih.gov/pubmed/18223027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/expphysiol.2007.040352
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