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Structural determinants for binding to angiotensin converting enzyme 2 (ACE2) and angiotensin receptors 1 and 2

Angiotensin converting enzyme 2 (ACE2) is a zinc carboxypeptidase involved in the renin–angiotensin system (RAS) and inactivates the potent vasopressive peptide angiotensin II (Ang II) by removing the C-terminal phenylalanine residue to yield Ang1–7. This conversion inactivates the vasoconstrictive...

詳細記述

保存先:
書誌詳細
出版年:Front Pharmacol
主要な著者: Clayton, Daniel, Hanchapola, Iresha, Thomas, Walter G., Widdop, Robert E., Smith, Alexander I., Perlmutter, Patrick, Aguilar, Marie-Isabel
フォーマット: Artigo
言語:Inglês
出版事項: Frontiers Media S.A. 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4311625/
https://ncbi.nlm.nih.gov/pubmed/25688208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2015.00005
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