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Angiotensin‐converting enzyme 2 catalytic activity in human plasma is masked by an endogenous inhibitor

Angiotensin‐converting enzyme 2 (ACE2) is thought to act in an opposing manner to its homologue, angiotensin‐converting enzyme (ACE), by inactivating the vasoconstrictor peptide angiotensin II and generating the vasodilatory fragment, angiotensin(1–7). Both ACE and ACE2 are membrane‐bound ectoenzyme...

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Pubblicato in:Exp Physiol
Autori principali: Lew, Rebecca A., Warner, Fiona J., Hanchapola, Iresha, Yarski, Michael A., Manohar, Jay, Burrell, Louise M., Smith, A. Ian
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Publishing Ltd 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7197901/
https://ncbi.nlm.nih.gov/pubmed/18223027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/expphysiol.2007.040352
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