Targeted chemotherapy overcomes drug resistance in melanoma

The emergence of drug resistance is a major obstacle for the success of targeted therapy in melanoma. Additionally, conventional chemotherapy has not been effective as drug-resistant cells escape lethal DNA damage effects by inducing growth arrest commonly referred to as cellular dormancy. We presen...

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Detalhes bibliográficos
Publicado no:Genes Dev
Main Authors: Yue, Jingyin, Vendramin, Roberto, Liu, Fan, Lopez, Omar, Valencia, Monica G., Gomes Dos Santos, Helena, Gaidosh, Gabriel, Beckedorff, Felipe, Blumenthal, Ezra, Speroni, Lucia, Nimer, Stephen D., Marine, Jean-Christophe, Shiekhattar, Ramin
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2020
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7197350/
https://ncbi.nlm.nih.gov/pubmed/32241802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.333864.119
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