Telomere length heterogeneity in ALT cells is maintained by PML-dependent localization of the BTR complex to telomeres

Telomeres consist of TTAGGG repeats bound by protein complexes that serve to protect the natural end of linear chromosomes. Most cells maintain telomere repeat lengths by using the enzyme telomerase, although there are some cancer cells that use a telomerase-independent mechanism of telomere extensi...

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Detalhes bibliográficos
Publicado no:Genes Dev
Main Authors: Loe, Taylor K., Li, Julia Su Zhou, Zhang, Yuxiang, Azeroglu, Benura, Boddy, Michael Nicholas, Denchi, Eros Lazzerini
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2020
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7197349/
https://ncbi.nlm.nih.gov/pubmed/32217664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.333963.119
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