Telomere length heterogeneity in ALT cells is maintained by PML-dependent localization of the BTR complex to telomeres

Telomeres consist of TTAGGG repeats bound by protein complexes that serve to protect the natural end of linear chromosomes. Most cells maintain telomere repeat lengths by using the enzyme telomerase, although there are some cancer cells that use a telomerase-independent mechanism of telomere extensi...

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Bibliografische gegevens
Gepubliceerd in:Genes Dev
Hoofdauteurs: Loe, Taylor K., Li, Julia Su Zhou, Zhang, Yuxiang, Azeroglu, Benura, Boddy, Michael Nicholas, Denchi, Eros Lazzerini
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Cold Spring Harbor Laboratory Press 2020
Onderwerpen:
Research Paper
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7197349/
https://ncbi.nlm.nih.gov/pubmed/32217664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.333963.119
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