Telomere length heterogeneity in ALT cells is maintained by PML-dependent localization of the BTR complex to telomeres

Telomeres consist of TTAGGG repeats bound by protein complexes that serve to protect the natural end of linear chromosomes. Most cells maintain telomere repeat lengths by using the enzyme telomerase, although there are some cancer cells that use a telomerase-independent mechanism of telomere extensi...

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Vydáno v:Genes Dev
Hlavní autoři: Loe, Taylor K., Li, Julia Su Zhou, Zhang, Yuxiang, Azeroglu, Benura, Boddy, Michael Nicholas, Denchi, Eros Lazzerini
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2020
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7197349/
https://ncbi.nlm.nih.gov/pubmed/32217664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.333963.119
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