Allantoin improves methionine-choline deficient diet-induced nonalcoholic steatohepatitis in mice through involvement in endoplasmic reticulum stress and hepatocytes apoptosis-related genes expressions

OBJECTIVE(S): Non-alcoholic steatohepatitis (NASH) is defined by steatosis and inflammation in the hepatocytes, which can progress to cirrhosis and possibly hepatocellular carcinoma. However, current treatments are not entirely effective. Allantoin is one of the principal compounds in many plants an...

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Bibliografski detalji
Izdano u:Iran J Basic Med Sci
Glavni autori: Komeili Movahhed, Tahereh, Moslehi, Azam, Golchoob, Mohammad, Ababzadeh, Shima
Format: Artigo
Jezik:Inglês
Izdano: Mashhad University of Medical Sciences 2019
Teme:
Original Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7196357/
https://ncbi.nlm.nih.gov/pubmed/32373294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22038/ijbms.2019.33553.8012
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