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Allantoin improves methionine-choline deficient diet-induced nonalcoholic steatohepatitis in mice through involvement in endoplasmic reticulum stress and hepatocytes apoptosis-related genes expressions

OBJECTIVE(S): Non-alcoholic steatohepatitis (NASH) is defined by steatosis and inflammation in the hepatocytes, which can progress to cirrhosis and possibly hepatocellular carcinoma. However, current treatments are not entirely effective. Allantoin is one of the principal compounds in many plants an...

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Detalles Bibliográficos
Publicado en:Iran J Basic Med Sci
Main Authors: Komeili Movahhed, Tahereh, Moslehi, Azam, Golchoob, Mohammad, Ababzadeh, Shima
Formato: Artigo
Idioma:Inglês
Publicado: Mashhad University of Medical Sciences 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7196357/
https://ncbi.nlm.nih.gov/pubmed/32373294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22038/ijbms.2019.33553.8012
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