Allantoin improves methionine-choline deficient diet-induced nonalcoholic steatohepatitis in mice through involvement in endoplasmic reticulum stress and hepatocytes apoptosis-related genes expressions

OBJECTIVE(S): Non-alcoholic steatohepatitis (NASH) is defined by steatosis and inflammation in the hepatocytes, which can progress to cirrhosis and possibly hepatocellular carcinoma. However, current treatments are not entirely effective. Allantoin is one of the principal compounds in many plants an...

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Pubblicato in:Iran J Basic Med Sci
Autori principali: Komeili Movahhed, Tahereh, Moslehi, Azam, Golchoob, Mohammad, Ababzadeh, Shima
Natura: Artigo
Lingua:Inglês
Pubblicazione: Mashhad University of Medical Sciences 2019
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7196357/
https://ncbi.nlm.nih.gov/pubmed/32373294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22038/ijbms.2019.33553.8012
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