Dysregulated Sp1/miR-130b-3p/HOXA5 axis contributes to tumor angiogenesis and progression of hepatocellular carcinoma

Angiogenesis, one of the hallmarks of cancer, is essential for both tumor growth and metastasis. However, its molecular mechanisms in hepatocellular carcinoma (HCC) are largely unknown. Here, we report the role of HOXA5 in tumor angiogenesis of HCC. Methods: The expression of miR-130b-3p and HOXA5 w...

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Veröffentlicht in:Theranostics
Hauptverfasser: Liao, Yadi, Wang, Chenwei, Yang, Zhiwen, Liu, Wenwu, Yuan, Yichuan, Li, Kai, Zhang, Yuanping, Wang, Yongjin, Shi, Yunxing, Qiu, Yuxiong, Zuo, Dinglan, He, Wei, Qiu, Jiliang, Guan, Xinyuan, Yuan, Yunfei, Li, Binkui
Format: Artigo
Sprache:Inglês
Veröffentlicht: Ivyspring International Publisher 2020
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7196310/
https://ncbi.nlm.nih.gov/pubmed/32373208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.43640
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